Depending on the location and severity of the fracture, condition of the neighboring joint, and general status of the patient, procedures may include open reduction and internal fixation with pins and plates, hemiarthroplasties, and total arthroplasties anastrozole vs tamoxifen 1 The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States, 2 Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, United States