Tyler, ET, Winer, J, Gotlib, M, et al lasix uses 0 mg Yes Improvement of 35 to 50 percent over placebo Headache, weight gain, and uterine bleeding; unknown effects on venous thromboembolic events, cardiovascular disease, and breast and uterine cancers Antidepressants SSRIs Citalopram Celexa 30 mg No No benefit over placebo Nausea, vomiting, diarrhea, insomnia, somnolence, anxiety, decreased libido, dry mouth, worsening depression, mania, suicidality, the serotonin syndrome, and the withdrawal syndrome; paroxetine and possibly other SSRIs decrease the activity of cytochrome P 450 enzymes, thereby decreasing the production of active metabolites of tamoxifen Soltamox, which may interfere with the anti breast cancer effects of tamoxifen Fluoxetine Prozac 20 mg Mixed Improvement of 24 percent over placebo in breast cancer survivors 30 mg Mixed No benefit among women without breast cancer Paroxetine Paxil 10 to 20 mg Yes Improvement of 30 percent over placebo in breast cancer survivors 12