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In arm A, blood samples were collected predose and at 11 predefined time points up to 48 h after intake of tolbutamide for determination of tolbutamide in plasma, at 11 predefined time points up to 12 h after intake of tolbutamide for determination of metoprolol in plasma, and finally at 13 predefined time points up to 24 h after the intake of tolbutamide for determination of chlorzoxazone in plasma stromectol 3 mg tablet PubMed 9425897
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